Treatment of Patient With Severe Nonproliferative DR and Good Vision
Overview
Current treatments and emerging therapies offer many possible options for the management of a patient with severe nonproliferative diabetic retinopathy-diabetic macular edema (NPDR-DME). This interactive case uses an engaging and challenging treatment sorting game to explore those options for a patient with NPDR-DME and provide strategies for an optimal outcome. Treatment decision points will provide opportunities to assess multiple strategies in the care plan to ensure an optimal outcome.
Target Audience
This activity has been designed to address the educational needs of retina specialists, retina fellows, and select comprehensive ophthalmologists.
Supporter Acknowledgment
This activity is supported by an independent medical educational grant from Regeneron Pharmaceuticals, Inc.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Assess the effects of intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy on diabetic retinopathy (DR)/diabetic macular edema (DME), as evidenced by recent data
- Differentiate among new and emerging strategies for more durable dosing of anti-VEGF to treat DR/DME
- Develop treatment plans for patients with DR/DME that are safe, effective, and tailored to patients’ clinical needs and personal preferences
Faculty & Disclosures
Presenting Faculty
Rishi P. Singh, MD, FASRS-Chairperson
Staff Surgeon and President
Cleveland Clinic Martin Hospitals
Professor of Ophthalmology
Cleveland Clinic Lerner College of Medicine
Stuart, FL
Steering Committee
Rishi P. Singh, MD, FASRS-Chairperson
Staff Surgeon and President
Cleveland Clinic Martin Hospitals
Professor of Ophthalmology
Cleveland Clinic Lerner College of Medicine
Stuart, FL
David M. Brown, MD, FACS
Director, Greater Houston Retina Research Center
Retina Consultants of Houston
Houston, TX
Carl D. Regillo, MD, FACS
Director, Retina Service
Wills Eye Hospital
Professor of Ophthalmology
Thomas Jefferson University
Philadelphia, PA
Disclosure of Relevant Financial Relationships
In accordance with the Accreditation Council for Continuing Medical Education’s (ACCME) Standards for Integrity and Independence in Accredited Continuing Education, Paradigm requires that all planners, faculty, and others who are in a position to control the content of this activity disclose all financial relationships with ineligible companies during the past 24 months.
All relevant relationships are identified and mitigated according to Paradigm policy prior to individuals assuming their roles, and are disclosed prior to learners’ engagement in the activity. Paradigm is committed to providing learners with high-quality accredited continuing education that promotes improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.
The content of this activity was independently reviewed to ensure that it is fair and balanced, scientifically rigorous, evidence based, and aligned with the public interest. All relevant relationships have been mitigated.
David M. Brown, MD, FACS
Consultant: Adverum Biotechnologies Inc; agtc; Alexion Pharmaceuticals, Inc; Annexon, Inc; Apellis Pharmaceuticals, Inc; Bayer Corporation; Beyeonics Surgical; Biogen; Boehringer Ingelheim International; Celltrion Inc; Chengdu Kanghong Pharmaceutical Group Co, LTD; Clearside Biomedical; Coherus BioSciences; Gemini Therapeutics; Glaukos Corporation; Horizon Therapeutics plc; IVERIC bio, Inc; Kodiak Sciences Inc; Laboratories Théa; Lineage Cell Therapeutics, Inc; Novartis AG; Optos; Platform Health; PPD Inc; Regeneron Pharmaceuticals Inc; RetinAl Medical AG; Ray Therapeutics; Samsung Bioepis; Senju Pharmaceutical Co; Stealth BioTherapeutics Inc; Verseon International Corporation; ZHUHAI SMILEBIOTEK CO LTD
Research Funding: Adverum Biotechnologies Inc; Alderya Thereapeutics, Inc; Alexion Pharmaceuticals, Inc; Alimera Sciences; Alkahest, Inc.; Amgen Inc; Annexon, Inc; Apellis Pharmaceuticals, Inc; Aura Pharmaceuticals Pvt Ltd; Bayer Corporation; Boston Image Reading Center; Boehringer Ingelheim International GmbH; Clearside Biomedical; Cleveland Clinic Foundation; EyePoint Pharmaceuticals, Inc; Gemini Therapeutics; Genentech, Inc; Graybug Vision Inc; Gyroscope Therapeutics Limited; Ionis Pharmaceuticals, Inc; Irenix Medical, Inc; IVERIC bio, Inc; Johns Hopkins; Kodiak Sciences Inc; Lowery Medical Research Group; LumiThera, Inc; Nanoscope Therapeutics, Inc; NEI/NH National Eye Institute/ National Health Institute; Neurotech Pharmacuticals, Inc; NGM Biopharmaceuticals, Inc; Novartis AG; Ocular Therapeutix, Inc; Ocuphire Pharma, Inc; OIRRC: Ocular Imaging Research and Reading Center; ONS: Outlook Therapeutics; Opthea; Opthotech Corp; OPTOS; Oxurion NV; Oyster Point Pharma, Inc.; Regeneron Pharmaceuticals Inc; REGENXBIO Inc; Roche; SamChunDang Pharm Co, Ltd; Samsung Bioepsis; Sandoz International GmbH; Santen Pharmaceutical Co., Ltd.; Senju Pharmaceutical Co; Stealth BioTherapeutics Inc; UNITY Biotechnology; Xbrane Biopharma; Zeiss International
Carl D. Regillo, MD, FACS
Consultant: 4D Molecular Therapeutics; Adverum Biotechnologies, Inc; Annexon, Inc; Apellis Pharmaceuticals, Inc; Aviceda Therapeutics; Clearside Biomedical; EyePoint Pharmaceuticals, Inc; Genentech, Inc.; Graybug Vision Inc; IVERIC bio, Inc; Kodiac Sciences Inc; Lineage Cell Therapeutics, Inc; NGM Biopharmaceuticals; Novartis AG; Ocugen, Inc; Stealth BioTherapeutics Inc
Research Funding: Adverum Biotechnologies, Inc; Allergan, Inc.; Annexon Inc; Clearside Biomedical; EyePoint Pharmaceuticals, Inc; Genentech, Inc.; IVERIC bio, Inc; Kodiac Sciences Inc; NGM Biopharmaceuticals; Regeneron Pharmaceuticals Inc; REGENXBIO Inc
Stocks: IVERIC bio, Inc; Ocugen, Inc
Rishi P. Singh, MD, FASRS
Consultant: Alcon; AsclepiX Therapeutics; Bausch Health Companies Inc.; Genentech, Inc.; Gyroscope Therapeutics Limited; Novartis AG; Regeneron Pharmaceuticals Inc
Paradigm Medical Communications, LLC staff members have no relevant financial relationships with ineligible companies to disclose.
Independent peer reviewer has no relevant financial relationships with ineligible companies to disclose.
CE Information
Physician Credit Designation Statement
Paradigm Medical Communications, LLC designates this enduring activity for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
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This accredited CME activity is designed using HTML5 web components. As you navigate the video using the supplied controls, the slides will sync to the speaker.
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PDF documents
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This educational activity may contain discussion of published and/or investigational uses of agents that are not approved by the FDA.
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Release Date: September 20, 2022
Expiration Date: September 20, 2023
Time to Complete: 15 minutes
Credit: 0.25 hour
Credit Types: AMA PRA Category 1 Credit™
Target Audience: Retina specialists, retina fellows, and select comprehensive ophthalmologists
Related Activities
This initiative is provided by Paradigm Medical Communications, LLC.
In collaboration with the American Association of Nurse Practitioners, American Academy of Physician Associates, California Academy of Family Physicians, Endocrine Society, National Minority Quality Forum, Global Education Group, and Salus University Pennsylvania College of Optometry.
Supporter Acknowledgment
This initiative is supported by an independent medical educational grant from Regeneron Pharmaceuticals, Inc.
Paradigm Medical Communications, LLC presents this resource for educational purposes only. Healthcare professionals are expected to employ their own knowledge and judgement during any discussion with, or treatment of, their patients.
For questions, technical support, or playback issues, please email us at contactus@paradigmmc.com.
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